One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process.